Grammar Reference
These words link opposing ideas, but the forms following them and the punctuation are different.
He is intelligent. However, he can't get a job.
In sentences using although, even though, in spite of and despite, the clauses can change position.
| 
       Clause 1* 
     | 
    Clause 2* | |
|---|---|---|
|  Although  Even though  | 
    
       he is intelligent,  | 
    
       he can't get a job. 
     | 
  
|  In spite of Despite  | 
     his intelligence, being intelligent,  | 
  |
*Clauses 1 and 2 can change position.